| 1832 | Nagase founded in Kyoto as a dyestuffs trading concern. Sales of dyestuffs, starches and funori seaweed. |
| 1893 | Established Osaka branch office. |
| 1898 | Head office switched to Osaka, branch office to Kyoto. |
| 1900 | Established business ties with Basel Chemical Co, of Switzerland. (now Ciba Specialty Chemicals Ltd.) |
| 1911 | Established Tokyo branch office. |
| 1917 | Inaugurated as Nagase Shoten Company with capital of \3 million. |
| 1923 | Established business ties with Eastman Kodak Co., of the United States. |
| 1930 | Concluded exclusive distributorship agreements with Union Carbide and Carbon Corp., of the United States. |
| 1940 | Established Nagoya branch office. |
| 1943 | Company name changed to Nagase & Co., Ltd. |
| 1964 | Listed Company shares on the Osaka Securities Exchange. |
| 1968 | Concluded an exclusive distributorship agreement with General Electric Co., of the United States. |
| 1970 | Established Nagase-CIBA Ltd. (now Nagase ChemteX Corp.) jointly with Ciba-Geigy Ltd. |
| 1970 | Listed Company shares on the Tokyo Stock Exchange. |
| 1971 | Established Nagase (Hong Kong) Ltd. |
| 1971 | Established Nagase America Corp. (now Nagase America Holdings Inc.) |
| 1971 | Established Engineering Plastics, Ltd. (now GE Plastics Japan Ltd.), jointly with General Electric Co. |
| 1974 | Established Nagase Landauer Ltd. jointly with Technical Operations, Inc., of the United States |
| 1975 | Established Nagase Singapore (Pte) Ltd. |
| 1980 | Established Nagase (Europa) GmbH |
| 1980 | Established Chang Fong Overseas Enterprises (Pte) Ltd. |
| 1982 | Established Nagase (Malaysia) Sdn. Bhd. |
| 1985 | Established Nagase & Co., Ltd., Seoul branch office. |
| 1988 | Established Nagase (Taiwan) Co.,Ltd. |
| 1989 | Established Nagase Science and Technology Foundation |
| 1989 | Established Canada Mold Technology Inc. |
| 1989 | Established Nagase (Thailand) Co., Ltd. |
| 1989 | Tokyo branch office became head office; adoption of Osaka/Tokyo two head office system. |
| 1990 | Established Sofix Corp. |
| 1990 | Setup the Nagase R&D Center in Kobe. |
| 1990 | Established joint venture Nagase Wahlee Plastics Corp. (Taiwan) |
| 1992 | Established London branch office. |
| 1997 | Established Nagase Philippines Corp. |
| 1997 | Established Shanghai Nagase Trading Co., Ltd. |
| 1997 | Established Nagase Engineering Service Korea Co., Ltd. |
| 1998 | Established P.T. Nagase Impor-Ekspor Indonesia. |
| 1998 | Established Shanghai Hua Chang Trading Co., Ltd. |
| 2001 | Closed the Seoul branch office, and established Nagase Korea Corp. |
| 2001 | Established Nagase Finechem Singapore (Pte) Ltd. |
| 2001 | Established Nagase Precision Plastics Shanghai Co., Ltd. |
| 2002 | Established Guangzhou Nagase Trading Ltd. |
| 2002 | Established a representative office in Hanoi, Vietnam |
| 2002 | Established Nagase ChemteX (Wuxi) Corp. |
| 2004 | Established Nagase International Electronics Ltd. |
| 2005 | Established Nagase Philippines International Services Corp. |
| 2006 | Acquired stock of semiconductor manufacturing equipment maker Pac Tech-Packaging Technologies GmbH |
| 2006 | Established Nagase India Private Ltd. |
| 2007 | Established Nagase Application Workshop |
| 2008 | Established Sakai Sales office. |
| 2008 | Established Nagase Vietnam Co.,Ltd. |
| 2009 | Established Dubai branch office. |
| 2012 | Acquired stock of Engineered Materials Systems Inc. |
| 2012 | Acquired stock of Hayashibara Co., Ltd. |